Infeksi COVID-19 pada Kehamilan dengan Insulin Dependent Diabetes Mellitus (IDDM) (Studi Kasus Puskesma Sape Kabupaten Bima)
Keywords:
Covid-19, Diabetes Mellitus Independen Insulin, Kehamilan, Th1, Th2Abstract
Research on pregnancies with insulin dependent diabetes mellitus (IDDM) infected with Covid- 19 is very limited. In pregnant conditions, there is a shift from Th1 to Th2 and physiological changes that make it very susceptible to being infected by Covid-19 in pregnancy, in addition to complaints that are similar between changes due to pregnancy and symptoms of Covid-19. The aim of this study was to Explain the effect of Covid-19 infection in pregnant women with IDDM. This study was conducted using a descriptive method of clinical and laboratory examination results of one pregnant patient aged 26 years with IDDM and infected with Covid-19 at the Sape Health Center. The variables in this study were the results of clinical and laboratory examinations of patients during treatment. All data were then analyzed descriptively according to the latest journal literature. Result of this study showed that Pregnant women with IDDM and infected with Covid-19 might have disorders of the lung organs in the form of pneumonia on X-rays, disturbances in laboratory test and minor clinical disorders. In addition, it is important to note that the presence of heart problems as indicated by disturbances in the rhythm of the post partum ECG. Covid-19 infection in pregnant women with IDDM can show mild or severe symptoms such as heart problems and further research is needed on the effect of this infection with a larger sample.
References
Alfaraj SH, Al-Tawfiq JA, Memish ZA, 2019. Middle East Respiratory Syndrome Coronavirus (MERS- CoV) Infection during Pregnancy: Report of Two Cases & Review of the Literature. J Microbiol Immunobiol Infect. 52(3): 501–503.
Angeletti S, Benvenuto D, Bianchi M, Giovanetti, M, Pascarella S et al, 2020. COVID-2019: the Role of the nsp2 and nsp3 in its Pathogenesis. J. Med. Virol. 2020, 1–5.
Ashokka B, Loh MH, Tan CH, Su LL, Young BE, Lye DC et al 2020. Care of the Pregnant Woman with COVID-19 in Labor and Delivery: Anesthesia, Emergency Cesarean Delivery, Differential Diagnosis in the Acutely Ill Parturient, Care of the Newborn, and Protection of the Healthcare Personnel. Am J Obstet Gynecol. 223(1): 66-74.
Breslin N, Baptiste C, Gyamfi-Bannerman C, Miller R, Martinez R et al, 2020. Coronavirus Disease 2019 Infection among Asymptomatic and Symptomatic Pregnant Women: Two Weeks of Confirmed Presentations to an Affiliated Pair of New York City Hospitals. American Journal of Obstetrics & Gynecology MFM. 2(2): 100-118.
Chen L, Li Q, Zheng D, Jiang H, Wei Y et al, 2020. Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China. Nengl j med. 382(25): 1-3.
Chen H, Guo J, Wang C, Luo F, Yu X et al, 2020. Clinical Characteristics and Intrauterine Vertical Transmission Potential of COVID-19 Infection in Nine Pregnant Women: a Retrospective Review of Medical Records. The Lancet. 395(10226): 809–815.
Coutard B, Valle C, de Lamballerie X, Canard B, Seidah N et al, 2020. The Spike Glycoprotein of The New Coronavirus 2019-Ncov Contains a Furin-Like Cleavage Site Absent in Cov of the Same Clade. Antivir Res. 176, 104742.
Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S, Biswas A et al, 2020. Coronavirus Disease 2019 (Covid- 19) Pandemic and Pregnancy. Am J Obstet Gynecol. 222(6): 521-531.
Dinas Kesehatan Kabupaten Sidoarjo. 2020. Laporan Kasus Kehamilan Dengan COVID-19 Agustus 2020.
Dong L, Tian J, He S, Zhu C, Wang J et al, 2020. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA. 323(18): 1846-1848.
Jawa Pos. 2020.RS di Sidoarjo Wajib Terima Bumil Positif. Jawa Pos; 18 Juli 2020.
Liang H and Acharya G, 2020. Novel Corona Virus Disease (Covid‐19) in Pregnancy: What Clinical Recommendations to Follow?. Acta Obs tet Gynecol Scand. 99 (4): 439-442.
Jiao J, 2020. Under the Epidemic Situation Of COVID-19, Should Special Attention to Pregnant Women be Given?. J Med Virol. 92: 1371-1372.
Li G and Clercq ED, 2020. Therapeutic Options for the 2019 Novel Coronavirus (2019-nCoV). Nat Rev Drug Discov. 19, 1449–14150.
Liu D, Li L, Wu X, Zheng D, Wang J et al, 2020. Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (Covid-19) Pneumonia: A Preliminary Analysis. American Journal of Roentgenology. 215(1): 127-132..
